Alex B Lentsch Selected Research

3- (4- (5- (4- (2- dihexylcarbamoylvinyl)phenyl)- 1H- imidazol- 4- yl)phenyl)acrylic acid

9/2006

Selectin inhibition modulates NF-kappa B and AP-1 signaling after liver ischemia/reperfusion.

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Alex B Lentsch Research Topics

Disease

35	Ischemia 01/2020 - 04/2002
20	Inflammation (Inflammations) 05/2013 - 04/2002
19	Reperfusion Injury 01/2016 - 04/2002
14	Hemorrhage 01/2022 - 06/2009
11	Wounds and Injuries (Trauma) 01/2021 - 09/2009
8	Hemorrhagic Shock 01/2020 - 07/2005
7	Acute Lung Injury 01/2020 - 07/2002
7	Lung Injury 01/2020 - 03/2007
7	Neoplasms (Cancer) 01/2018 - 07/2002
6	Prostatic Neoplasms (Prostate Cancer) 02/2011 - 07/2002
5	Pneumonia (Pneumonitis) 01/2020 - 09/2014
4	Infections 09/2014 - 05/2008
4	Hypoxia (Hypoxemia) 12/2013 - 09/2007
3	Fibrosis (Cirrhosis) 03/2015 - 07/2011
2	Burns 01/2020 - 03/2012
2	Necrosis 12/2019 - 04/2015
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2019 - 03/2015
2	Cystic Fibrosis (Mucoviscidosis) 09/2014 - 05/2013
2	Encephalitis (Encephalitis, Rasmussen) 12/2013 - 10/2013
2	Brain Injuries (Brain Injury) 12/2013 - 10/2013
2	Non-alcoholic Fatty Liver Disease 07/2011 - 04/2010
2	Sepsis (Septicemia) 07/2009 - 03/2008
2	Shock 06/2008 - 01/2006
2	Hypothermia 01/2007 - 04/2002
1	Liver Diseases (Liver Disease) 03/2015
1	Portal Hypertension 03/2015
1	Liver Failure 03/2015
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2014
1	Traumatic Brain Injuries (Traumatic Brain Injury) 09/2014

Drug/Important Bio-Agent (IBA)

15	CytokinesIBA 10/2020 - 05/2003
10	NF-kappa B (NF-kB)IBA 03/2012 - 07/2002
8	CXC ChemokinesIBA 04/2015 - 04/2004
7	ChemokinesIBA 12/2019 - 07/2002
6	EnzymesIBA 01/2017 - 04/2009
6	LigandsIBA 01/2015 - 10/2006
6	Transcription Factors (Transcription Factor)IBA 03/2012 - 04/2004
5	Interleukin-6 (Interleukin 6)IBA 01/2021 - 07/2009
5	Proteins (Proteins, Gene)FDA Link 01/2018 - 04/2002
4	Chemokine CCL22IBA 01/2020 - 02/2010
4	salicylhydroxamic acid (SHAM)IBA 10/2011 - 04/2005
3	Interleukin-10 (Interleukin 10)IBA 01/2021 - 02/2003
3	Crystalloid SolutionsIBA 01/2020 - 02/2010
3	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2017 - 05/2013
3	Ringer's LactateIBA 12/2014 - 02/2010
3	Phenobarbital (Luminal)FDA Link 09/2014 - 10/2011
3	Biomarkers (Surrogate Marker)IBA 12/2013 - 10/2006
3	SpermidineIBA 09/2012 - 04/2009
3	SpermineIBA 09/2012 - 04/2009
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 07/2011 - 12/2002
3	CopperIBA 07/2011 - 12/2002
3	Antigen Receptors (Antigen Receptor)IBA 02/2011 - 07/2002
3	PPAR gammaIBA 06/2009 - 01/2008
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2009 - 01/2007
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 09/2006 - 04/2002
2	SolutionsIBA 01/2022 - 10/2011
2	Hemoglobins (Hemoglobin)IBA 10/2020 - 07/2010
2	p38 Mitogen-Activated Protein KinasesIBA 01/2020 - 10/2012
2	Saline SolutionIBA 01/2020 - 01/2018
2	Amitriptyline (Elavil)FDA LinkGeneric 01/2017 - 03/2015
2	AcidsIBA 01/2017 - 05/2013
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2015 - 07/2002
2	CeramidesIBA 09/2014 - 05/2013
2	Phosphopyruvate Hydratase (Enolase)IBA 12/2013 - 10/2013
2	AlbuminsIBA 03/2013 - 03/2007
2	AcetyltransferasesIBA 09/2012 - 04/2009
2	Oxygen (Dioxygen)IBA 07/2012 - 09/2007
2	LipopolysaccharidesIBA 03/2012 - 03/2007
2	Alanine Transaminase (SGPT)IBA 07/2011 - 04/2009
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2010 - 05/2009
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2007 - 01/2006
2	NF-KappaB Inhibitor alphaIBA 01/2007 - 04/2005
1	AntibodiesIBA 01/2020
1	Matrix Metalloproteinase 13IBA 01/2019
1	Arachidonic Acid (Vitamin F)IBA 10/2018
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2016
1	SphingolipidsIBA 06/2015
1	plerixafor FDA Link 04/2015
1	CXCR4 Receptors (CXCR4 Receptor)IBA 04/2015
1	CollagenIBA 03/2015
1	Carbon Tetrachloride (Tetrachloromethane)IBA 03/2015
1	Baclofen FDA LinkGeneric 01/2015
1	ImmunosorbentsIBA 12/2014
1	Neutralizing AntibodiesIBA 12/2014
1	CC ChemokinesIBA 12/2014
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 12/2014
1	Substance PIBA 09/2014
1	Fingolimod Hydrochloride (FTY720)FDA Link 09/2014
1	Acid CeramidaseIBA 09/2014
1	SphingosineIBA 09/2014
1	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 09/2014
1	EndotoxinsIBA 02/2014

Therapy/Procedure

13	Resuscitation 01/2022 - 06/2009
10	Transplantation 01/2012 - 05/2005
4	Liver Transplantation 01/2020 - 07/2011
4	Ligation 08/2010 - 03/2008
3	Punctures 07/2009 - 03/2008
2	Hepatectomy 01/2016 - 01/2015
2	Therapeutics 03/2015 - 07/2005
1	Intravenous Administration 12/2014
1	Length of Stay 09/2014